cellular stress increases progressively with aging in mammalian tissues. dementia is a growing concern due to the aging process of the western societies. one measure of cellular aging is the telomere. moisturizing of the skin is recognized as the first anti-aging skin care. telomere shortening is associated with the risk of many aging-related diseases. aerobic exercise has been suggested to ameliorate aging-related decline in humans. the aging eye appears to be at considerable risk from oxidative stress. sedentary aging results in a diminished rapid cutaneous vasodilator response to local heating. caloric restriction is widely used to study aging processes. oxidative stress is widely thought to underpin many aging processes. menopause is a sign of aging in the woman. a multivariate logistic model was run for our global successful aging measure. the pathogenesis of aging-associated structural changes is not completely understood. there are a number of mechanisms suggested to explain age-related endothelial dysfunction. there is consistent evidence for a central role of mitochondrial dysfunction in these pathologies. mitochondrial dysfunction is associated with age-related degenerative diseases. how mitochondrial dysfunction causes cell degeneration is not well understood. decreases in fa correlated well with neuropsychological dysfunction. akt inhibition either by chemical inhibitors or small interfering rnas induced telomere dysfunction. with age comes an increased risk for chronic mental health disorders. the comparison of women who underwent bilateral oophorectomy with referent women provided evidence for a sizeable neuroprotective effect of estrogen before age @number@ years. evidence for cholinergic dysfunction in very early stages of neurodegeneration like mild cognitive impairment ( mci ) is inconclusive. there was no statistically significant age or gender effect. slowing of movement with aging is inevitable. fat transfer for the aging face is an increasingly popular method for facial rejuvenation. the aging eye appears to be at considerable risk from oxidative stress. lactase gene expression declines with aging in the majority of humans worldwide. reproductive cessation is perhaps the earliest aging phenotype that humans experience. the complex etiology of aging is a challenge to the researchers. the brain aging process is not uniform. osteoporosis in elderly men is becoming an important health issue with the aging society. late onset hypogonadism is a common condition in aging males. environmental factors are key triggers in timing endocrine aging with implications for eventual disease. the effects of aging were determined by testing for linear trends using regression analysis. it makes obvious that the stochastic mechanism of aging is incorrect. diagnostic imaging techniques guided the decision to use the posterior episcleral buckling procedure. facelift is the cornerstone procedure for the rejuvenation of the aging face. positron emission tomography imaging has been used to compare resting brain glucose metabolism. transgenerational telomere erosion is therefore the material basis of aging at the species level. menopause is a key point moment in the specific aging process of women. maintaining optimal nutritional status is therefore crucial for aging in good health. antiaging medicine is nowadays an equivocal topic frequently used in geriatric medicine. the ability of organisms to adapt to their environment during aging is altered. erectile dysfunction is a common disorder among aging males. senescence is a form of cellular aging that limits the proliferative capacity of cells. the poor functional status of aging combat-exposed veterans is of particular concern. molecular mechanisms underlying t-cell aging are beginning to be understood. doppler flow imaging has been the mainstay of diagnosis. posterior vitreous detachment is a common phenomenon in the aging eye. adult stem cell function declines during the aging process of an organism. late-onset hypogonadism is a relatively common conditions affecting the aging male. aging is a complex physiological process that poses considerable conundrums to rapidly aging societies. benign prostatic hyperplasia is a major health concern for aging men. one of the main manifestations of vascular aging is the development of atherosclerotic lesions. the consequences of short-duration intermittent exercise on heat storage with aging are unclear. human aging is associated with the deterioration of long-lived proteins. the underlying mechanisms of aging-exacerbated effects remain unknown. the biological aging process is commonly associated with increased risk of cardiovascular diseases. carotenoids can serve as marker substances for the complete antioxidative network of human skin. lipids in the skin are the most diverse in the entire human body. autologous human keratinocytes forming sheet grafts are approved as skin substitutes. the contribution of autophagy to age-related changes in the human skin is unclear. locally administered bh4 increases vasoconstriction through adrenergic mechanisms in aged human skin. the majority of patients with major depressive disorder suffer from significant executive dysfunctions. mild cognitive changes ( especially executive dysfunction ) have been documented in many studies as well. our findings support the use of multifractal analysis to assess aging-related microvascular dysfunction. the same therapeutic modalities can be used to treat erectile dysfunction after radical prostatectomy. cardiovascular disease risk factors may be important correlates of age-related auditory dysfunction. endothelial dysfunction in essential hypertension is an independent predictor for future cardiovascular events. the incidence of postoperative cognitive dysfunction was observed less often than expected. anesthesia-related postoperative cognitive dysfunction ( pocd ) leads to morbidity in the elderly. it has been implicated with dysfunction in primary cilia. mitochondrial dysfunction is a common hallmark of ageing-related diseases involving neurodegeneration. the origin of this ovarian dysfunction is still debatable. ventricular dysfunction is frequently encountered in fontan patients. lipid oxidation products that accumulate in aged tissues may generate protein dysfunction. low levels of tfam lead to first-phase oxphos dysfunction. mitochondrial dysfunction plausibly underlies the aging-associated brain degeneration. erectile dysfunction ( ed ) is a common disorder among aging males. the key event caused by wrn gene mutation is the dysfunction of telomeres. telomere dysfunction in ws is closely correlated with abnormality in tumorigenesis. the increased functional connectivity within the frontal network was associated with executive dysfunction. our data suggest that presynaptic snare dysfunction forms part of the synaptopathology of ad. cardiac autonomic dysfunction is a serious condition in the elder subjects. presepsin concentrations were significantly increased in patients with kidney dysfunction. there was a predominance of dysfunctional variants in cases compared to controls. microalbuminuria is a marker of kidney dysfunction frequently related to an inflammatory event. thyroid dysfunction is common in the general population especially in women. force to distance analysis demonstrated a dependence on age. the population ageing is a challenge for health professionals. exercise habit in middle age was associated with low prevalence of sarcopenia in older age. recent advances of mobile technologies have made mobile devices a promising tool to manage patients ' own health status through services like telemedicine. multiple regression analysis was used to adjust for chronologic age. asthma is a disease of all ages. advancing age is associated with increased mortality even after controlling for preexisting morbidity. old age vmrs are significantly enriched for neurotransmission pathways. increased age is closely related with aforementioned alterations. single-agent chemotherapy would be a good choice for elderly lung cancer.