there were a number of cases ( @percent@ [ 22 / 1726 ] ) which had > 2 factors assigned
measurements were performed in the subfoveal position and at @number@ [μm] nasally and temporally
methods : a walking version of the trail making test ( walking executive function task , [ weft ] ) was used
results : ten of @number@ eligible patients consented over @number@ months [ all female , mean age @number@ years ( sd @number@ ) ]
[ journal of psychosocial nursing and mental health services , 55 ( @number@ ) , 7-10 . ]
[ full article available at @url@ 
normal human dermal fibroblasts were treated with eucalyptus globulus at concentrations ranging from @number@ to @number@ [μg] / ml after uvb or non-uvb irradiation
hum brain mapp 39 : 522-531 , @number@ [©] @number@ wiley periodicals , inc
exposures : maternal residential pm2.5 ( particles with an aerodynamic diameter ≤2.5 [μm] ) exposure during pregnancy
mad experienced by illegitimate children was @number@ y ( @percent@ ci : [ @date@ @number@ ] ) shorter than of legitimate children
have yet been reported in varicella-zoster virus ( vzv ; also known as human herpesvirus @number@ [ hhv-3 ] )
sarcopenia developed at a higher rate with incident ui ( adjusted odds ratio [ or ] @number@ @percent@ ci @number@.0-2.9 )
( progression of early subclinical atherosclerosis [ pesa ] ; nct01410318 )
mid-adulthood hypertension was associated with @percent@ ( @percent@ confidence interval [ ci ] @number@ @date@ ) increased dementia risk among women but not men
[ journal of psychosocial nursing and mental health services , 55 ( @number@ ) , 27-30 . ]
a total of @number@ subjects ( mean age @number@ years [ range @number@ to @number@ ] ; @percent@ men ) were evaluated retrospectively
[ formula : see text ] peak and ci max were related to exercise cerebral oxygenation-perfusion and cognitive function ( p < 0.005 )
in the all sample , cognitive functions correlated with [ formula : see text ] peak , ci max and cerebral oxygenation-perfusion
[ res gerontol nurs
@number@ 10 ( @number@ ) : 205-214 . ]
intervention : skeletal muscle biopsies obtained during a primed-continuous infusion of l- [ ring-13c6 ] - phenylalanine
a long post-menopausal period was a risk factor for large soft drusen ( ≥ @number@ [μm] )
results : plasmodium knowlesi parasitemia correlated with age ( spearman's correlation coefficient [ rs ] = @number@ p < @number@ )
in falciparum malaria , angiopoietin-2 increased with age , independent of parasite biomass ( histidine-rich protein @number@ [ hrp2 ] )
arsenic levels were @number@ @number@ and @number@.7 [μg] / l at the 50th , 75th , and 90th percentiles , respectively
results & conclusion : the minimum inhibitory concentration of n12 d and n23 d against mrsa was @number@.9-9.8 and @number@ [μm] , respectively
n12 d was found to inhibit mrsa biofilm thickness from @number@ to @number@ [μm] as observed by confocal microscopy
[ full article available at @url@ 
peroxisome proliferator-activated receptor [γ] ( pparγ ) is a ligand-activated transcription factor with an important role in lipid metabolism , inflammation and cardiovascular diseases
results : participants had a median age of @number@ years [ iqr 54-61 ] , @percent@ were men , and @percent@ were african american
the control condition was @number@ [°c] and @percent@ rh
copyright [©] @number@ pathological society of great britain and ireland
here , we utilized efad carriers [ 5xfad trigonella foenum-graecum seed extract has demonstrated hormone modulatory activity , providing biological plausibility for relieving menopausal symptoms
copyright [©] @number@ john wiley & sons , ltd
[ journal of psychosocial nursing and mental health services , 55 ( @number@ ) , 13-17 . ]
results : the estimated normal average rnfl thickness change over time was @number@ ± @number@ [μm] / year ( p < @number@ )
the median age was @number@ years ( interquartile range [ iqr ] 69-80 ) , @percent@ were women and @percent@ had oab syndrome
cancer @number@ ; 123 : 4207-4214 . [©] @number@ american cancer society
@number@ [ @number@.2-4.4 ] ) , and lower alpha power and peak frequency ( hr [ @percent@ ci ] = @number@ [ @number@.3-1.0 ] resp
@number@ [ @number@.4-1.0 ] ) were associated with clinical progression over time
at the end of this review , we discuss remaining key questions in this area and propose new research approaches . [©] @number@ american physiological society
discrimination was not associated with poorer verbal fluency ( b = @number@ @percent@ ci [ @number@ @number@ ] ) at follow-up
obese males were @percent@ [ odds ratio : @number@ ( @number@.4-2.7 ) ] more likely to be hypertensive compared to normal weight males
mean subfoveal choroidal thickness ( sfct ) was 282±49 [μm]
objective : to compare the safety , efficacy , and duration of response of daxibotulinumtoxina with onabotulinumtoxina and placebo [ www.clinicaltrials.gov nct02303002 ]
the average ila was @number@.45 [°] ± @number@ and @number@.25 [°] ± @number@ for males and females , respectively ( p < 10-25 )
in @number@ patients , we assessed glucose kinetics with an infusion of @number@ , 6- [ 2h2 ] glucose
here , we examine how β-cell [ ca 
background : mild hyperphosphatemia is a putative risk factor for cardiovascular disease [ cvd ] , loss of kidney function , and mortality
self-perceived worsened health was positively associated with overall ea ( odds ratio [ or ] @number@ ( @number@ @number@ )
older adults who have lived in the u.s . longer had a higher risk of financial exploitation ( or @number@ [ @number@ @number@ ] )
hypertension increased the rate of all fractures by @percent@ after adjustment for covariates [ airr : @number@ ( @number@ @number@ ) ]
the restricted and more recent evolutionary appearance of pol ν ( in comparison to pol [θ] ) supports such a specialized role
several examples are brain-penetrant and exhibit balanced multitargeted in vitro activity in the low [μm] range
randomization was stratified for age , function , and symptom severity ( victorian institute of sports assessment-achilles [ visa-a ] )
findings revealed pfd during childhood to be significantly associated with crp ( or = @number@ @percent@ ci [ @number@ @number@ ] )
background : red blood cells collected in can be stored for up to @number@ days at @number@ [°c] in additive solution
twenty asymptomatic adults ( [ formula : see text ] = @number@ ) performed multiple @number@ m timed up and go
relative sensor kinematics accuracy ( i joint ) varied between @number@.6 [°] and @number@.6 [°] over the same tasks
we found that coating the culture surface coated with @number@ [μg] cm alzheimer's disease and related dementias ( adrd ) affect over @number@ million americans
objective : a disintegrin and metalloproteinase adam17 ( tumor necrosis factor-α [ tnf ] - converting enzyme ) regulates soluble tnf levels
[ bmb reports @number@ 50 ( @number@ ) : 345-354 ]
methods : after pre-treatment with @number@ pmklotho for @number@ h , huvecs were stimulated with @number@ [μg] / ml ox-ldl for @number@ h. 
@number@.9 ( @number@ ) ] , cfu-ecs [ median ( iqr ) : @date@ ( @number@ ) , @date@ ( @number@ ) , iii
proteins @number@ 85 : 1190-1211 . [©] @number@ wiley periodicals , inc
[ bmb reports @number@ 50 ( @number@ ) : 269-274 ]
participants [ n = @number@ mean age ( range ) = @number@ ( 65-96 ) years ] completed interviewer-administered questionnaires and objective measures of mobility
of these , @percent@ [ @number@.36%-1.77 % ] had unilateral pseudophakia and @percent@ [ @number@.81%-3.37 % ] had bilateral pseudophakia
hum brain mapp 38 : 3039-3051 , @number@ [©] @number@ the authors human brain mapping published wiley by periodicals , inc
women positive for cytology [ atypical squamous cells of undetermined significance ( asc-us ) or worse ] or hrhpv were referred for colposcopy
hum brain mapp , @number@ [©] @number@ wiley periodicals , inc
hum brain mapp 38 : 3141-3150 , @number@ [©] @number@ the authors human brain mapping published by wiley periodicals , inc
hum brain mapp 38 : 3141-3150 , @number@ [©] @number@ wiley periodicals , inc
the pathogenic repeat expansion [ ggggcc ] posterior reversible encephalopathy syndrome ( pres ) is diagnosed based on neuroradiological findings
dementia incidence ( @number@ of @number@ men [ @percent@ ] ) was not different among the @number@ study arms
fifty-six participants [ age : 70 ( @number@ ) years ; @percent@ female ] were included in this study
results : median growth hormone peak was @number@ [μg] / l and median cortisol peak was @number@ [μg] / d l
apolipoprotein e ( apoe ) [ε4] has been associated with smaller hippocampal volumes in healthy aging , while findings in young adults are inconclusive
crf was assessed by measuring peak oxygen uptake ( [ formula : see text ] )
recently , a number of drugs and substances [ in addition to insulin and its mimics ] have shown promising potentials against diabetes-induced brain injury
mvpa , was also associated with a reduced decline in cognitive ability ( rate ratio @number@ [ @number@.75-0.95 ] )
hum brain mapp 38 : 2751-2771 , @number@ [©] @number@ wiley periodicals , inc
one beer had sulfuric and fecal off-flavors ; it was bright with the original extract of @number@.3 [°] plato
the second beer , with an original extract of @number@.6 [°] plato , was dark and very acidic , resembling lambic
the third beer contained traces of carbon dioxide bubbles , was light brown and slightly bitter , with an original extract @number@.4 [°] plato
we tested the effects of an oral antioxidant treatment ( alpha lipoic acid [ ala ] ) on af recurrence post-ca
crude and adjusted odds ratios ( or [ @percent@ confidence interval ] ) were calculated
developmental dynamics 246 : 359-367 , @number@ [©] @number@ wiley periodicals , inc
the mean alm was @number@ kg [ standard deviation ( sd ) : @number@ ]
underweight [ body mass index < @number@ kg / m2 ] was not associated with the presence of aspiration
hum brain mapp 38 : 2589-2598 , @number@ [©] @number@ wiley periodicals , inc
cancer @number@ ; 123 : 2551-60 . [©] @number@ american cancer society
the accelerated hydrothermal aging testing ( at @number@ [°c] , 2-bars pressure ) was conducted up to @number@ h. 
there was no association between baseline prediabetes and disability [ or = 1.27 ( @percent@ ci @number@.91-1.78 ) ]
across the subcortical areas an increase of [ formula : see text ] values is observed , most likely indicating a loss of myelin
the viscosity of the formulations at @number@ [°c] ranged from @number@ @number@ to @number@ @number@ cp
the impact of mutations on hbsag-secretion was assessed by measuring the ratio [ secreted / intracellular hbsag ] until day @number@ post-transfection
results : eleven men and @number@ women with a mean age of @number@ years [ 60-87 ] were included in the study
average operative time was 86minutes [ 61-110 ] and blood loss was estimated as minor in all the cases
with a @number@ months average follow-up [ 6-20 ] , no cases of infection or mechanical complication was reported
hum brain mapp 38 : 2398-2407 , @number@ [©] @number@ wiley periodicals , inc
etheno ( [ε] ) dna base adducts are highly mutagenic lesions produced endogenously via reactions with lipid peroxidation ( lpo ) products
[ bmb reports @number@ 50 ( @number@ ) : 164-174 ]
[ res gerontol nurs
@number@ 10 ( @number@ ) : 17-24 . ]
meanwhile , near visual acuity and cognition also showed unique environmental correlation , r e = @number@ [ @percent@ ci : @number@ @number@ ]
[ journal of gerontological nursing , @number@ ( @number@ ) , 23-29 . ]
background the fastest growing segment of the population is those age [≥80] who have the highest stroke incidence
during a median [ iqr ] follow-up time of 36 months , @number@ ( @percent@ ) stroke / tia events were recorded
hum brain mapp 38 : 1875-1893 , @number@ [©] @number@ wiley periodicals , inc
cct decreased from @number@ ± @number@ [μm] preoperatively to @number@ ± @number@ [μm] ( p < @number@ ) at @number@ months
[ ophthalmic surg lasers imaging retina
@number@ ; 48 : 79-82 . ]
hum brain mapp 38 : 2128-2149 , @number@ [©] @number@ wiley periodicals , inc
hum brain mapp 38 : 2026-2036 , @number@ [©] @number@ wiley periodicals , inc
trial registration number : [ clinicaltrials.gov : nct02802371 ] registered in @date@
we applied [ reactive oxygen species ( ros ) play a major role in both chronological aging and photoaging
the estimate was attenuated after full adjustment ( or = @number@ [ @percent@ ci : @number@ @number@ ] )
two hundred autopsied , non-atrial fibrillation hearts ( @percent@ deriving from females ) whose donors were a mean of [@number@.6±17.6] years old were investigated
cancer discov ; 7 ( @number@ ) ; 165-76 ..y [©] 2016 aacr.this article is highlighted in the in this issue feature , p ..y @number@ 
substantial variability is associated with laboratory measurement of serum total 25-hydroxyvitamin d [ 25 ( oh ) d ]
copyright [©] @number@ john wiley & sons , ltd
purpose : a self-paced maximal exercise protocol has demonstrated higher [ formula : see text ] values when compared against traditional tests
food insecurity is associated with peripheral arterial disease among older adults ( adults adjusted odds ratio , @number@ [ @percent@ ci @number@ @date@ )
results : the rate of baseline hypertension was @percent@ in this cohort and the mean nail selenium level is @number@.413±0.183 [μg] / g
olfactory sensitivity has been assessed by [«] sniffin ' sticks [»]
the average men 's arch also had a more acute angle at the apex ( @number@.7 [°] vs @number@.7 [°] p < @number@ )
the observed trajectory of [ 18f ] - fdg alterations deviated from our proposed hypothesis of gradual decreases with worsening amyloidosis
moreover , [ 18f ] - fdg uptake did not correlate to measures of ex vivo amyloid burden
aberrant [α-synuclein] ( α-syn ) accumulation has been shown to impair mitochondrial function by reducing mitochondrial membrane potential ( mmp )
time-frequency analyses conducted at source level found variations in both [θ] and [γ] ranges across age
history of psychiatric hospitalization was associated with moderate or greater illicit drug symptoms ( adjusted odds ratio [ aor ] = @number@ @number@.0-3.6 )
patients received subcutaneous teriparatide @number@ [μg] daily for up to @number@ months
survival at @number@ months was unaffected ( adjusted hazard ratio [ ahr ] , @number@ @percent@ ci , @number@.54-1.08 ; p = @number@ )
the novel method enabled determination of each pls species in human plasma at the concentrations of @date@ .6! [μm]
hum brain mapp 38 : 1588-1603 , @number@ [©] @number@ wiley periodicals , inc
this mini-review examines sex differences in the immune response to experimental stroke and its implications for therapy development . [©] @number@ wiley periodicals , inc
furthermore , this nascent examination of the i-ssst suggests a possible alternative for inducing stress in the laboratory . [©] @number@ wiley periodicals , inc
we also describe sex-related findings from the enigma consortium , and ongoing efforts to better understand sex differences in brain circuitry . [©] @number@ the authors
these together help delineate the different roles of sex and gender in relation to risk vs protective mechanisms . [©] @number@ wiley periodicals , inc
copyright [©] @number@ pathological society of great britain and ireland
[ bmb reports @number@ 49 ( @number@ ) : 671-680 ]
[ bmb reports @number@ 50 ( @number@ ) : 43-48 ]
spray use was lower in the west than in the northeast ( @number@ [ @number@.58-0.97 ] )
stent type may influence the benefit of prolonged dapt . [©] @number@ wiley periodicals , inc
nursing home residence , female sex , and greater number of drugs predict non-rational long-term use of ppi . [©] @number@ the authors
results : cvd was significantly , negatively related to cps ( β = @number@ @percent@ ci [ @number@ @number@ ] )
cps was significantly , positively related to an ef composite score ( β = @number@ @percent@ ci [ @number@ @number@ ] )
cvd was significantly , negatively related to the ef composite score ( β = @number@ @percent@ ci [ @number@ @number@ ] )
in particular , [ @number@ ] - shogaol markedly and dose-dependently inhibited trpc5 currents with an ic50 of value of ~18.3 µm
furthermore , the strong dose-dependent activation of trpa1 currents by [ @number@ ] - shogaol was abolished by a-967079 ( a selective trpa1 inhibitor )
patients with healed fracture ( age @number@.0±12.7 [@number@.0±12.7sd] ) were older ( p < 0.0001 ) than patients with nonunion ( age @number@.2±13.4 [@number@.2±13.4sd] )
results : cocaine at @number@ and @number@ [μm] significantly increased human astrocyte proliferation
modern techniques using fourier spectral analysis of the reflected light enhance axial resolution to 5-10 [μm] , almost matching classic histological sections
median age was @number@ years [ interquartile range ( iqr ) @number@ ] with a slight predominance ( @number@ % ) of females
perceived isolation was significantly related with social disconnectedness ( standardized coefficient [ r ] = @number@ )
we identify nuclear respiratory factor @number@ and peroxisome proliferator-activated receptor [γ] coactivator 1α as regulators of human telomere transcription
specimens were either auto-polymerized or dual-cured ( except p21 ) and stored in water at @number@ [°c] for @number@ day prior to measurement
conclusions : emotional support may increase well-being among spanish-speaking latina cancer survivors by reducing cancer fatalism.copyright [©] @number@ john wiley & sons , ltd
results : the prevalence of multimorbidity in this population was @percent@ ( @percent@ confidence interval [ ci ] , 65%-68 % )
copyright [©] @number@ john wiley & sons , ltd
our results suggest that high shbg may also be a risk factor for hyperkyphosis . [©] @number@ american society for bone and mineral research
total ams score increased [ mad 9·35 ( 5·65 , 13·07 ) , p < 0·001 ] , reflecting worse qol
copyright [©] @number@ john wiley & sons , ltd
copyright [©] @number@ pathological society of great britain and ireland
their ages ranged from @number@ to @number@ years ( @time@ ± @number@ years [ mean ± sd ] )
ambient pm2.5 ( particulate matter with aerodynamic diameter ≤ @number@ [μm] ) is an emerging determinant of glucose dysregulation
( @number@ % vs @number@ % or @number@ @number@ % ci [ @number@ @number@ ] p = @number@ )
ad transgenic mice were fed either folate-deficient or control diets and gavaged daily with water or folic acid ( @number@ [μg] / kg )
further information and enquiries can be made to [ sagesurvey@who.int ] or the corresponding author
conclusion : these results expand upon previous observations indicative of age-related reductions in intramuscular [ atp ] and dietary protein intake
results : uc had the highest contact angle ( @number@.4 [°] ) , whereas hf10 showed the lowest contact angle ( @number@.5 [°] )
aging significantly reduced lumbar lordosis by @number@.2 [°] and sacrum orientation by @number@.6 [°] during standing in all subjects
with aging , the lumbar rof decreased by @number@.7 [°] , whereas the pelvic rof compensated for this effect and increased by @number@.0 [°]
the radiopharmaceutical [ ( @number@ ) c ] abp688 allows for in vivo quantification of mglur5 availability using positron emission tomography ( pet )
results : we found the highest [ ( @number@ ) c ] abp688 bpnd in the lateral prefrontal and anterior cingulate cortices
fifteen male , age-matched former professional non-contact sport athletes ( mean age @number@ [ sd @number@ ] years ) served as controls
a total of @number@ lesions were treated with cream puva using the digital phototherapy device skintrek ( [®] ) pt3
descriptive statistics and linear [ spearman rank-order ( rs ) ] and nonlinear ( goodness-of-fit ) correlations were performed
wlr was calculated by the formula [ formula : see text ]
the mean deficit was @number@ ( median : @number@ ) [€] per patient , range : - @number@ , 470-75 , 144 [€]
psychology and aging , @number@ 677-689 ]
we carried out a sensory organization test and limits of stability with the neurocom smart balance master ( [®] ) posturography platform
t1-11 [ n6- ( 4-hydroxybenzyl ) adenosine ] , isolated from a chinese medicinal herb gastordia elata , is an adenosine a2a receptor agonist
all compounds were tested over a 24-h period at @number@ and @number@ [μm] , in duplicate , with cytotoxicity measured using the mtt assay
retesting these compounds at @number@ @number@ and @number@ [μm] using the same exposure protocol yielded consistent results as compared with the primary screen
underweight was a risk factor for higher mortality caused by infections ( hr = @number@ [ @percent@ ci = @number@ @date@ ] )
results : twenty-two participants enrolled : @number@ ( mean [ sd ] age : @number@ [ @number@ ] ) completed cr
mean osteon orientation was @number@.1 [°] ( 90 ° being longitudinal )
serum 25-hydroxyvitamin d [ 25 ( oh ) d ] levels were determined using chemiluminescent immunoassay
to investigate the detailed binding procedures , molecular dynamics simulations were conducted on the hybrid [ @number@ + @number@ ] form-one human telomeric intra-molecular g-quadruplex
deprivation-related inequities among women significantly favoured groups with higher ses ( hii = @number@ [ @number@ ; @number@ ]
no such deprivation-related inequities were seen among men ( hii = @number@ [ @number@ ; @number@ ] )
lysosomal-β-galactosidase ( glb1 ) hydrolyzes β-galactose from glycoconjugates and is the origin of senescence-associated β-gal activity ( [sa-β-gal] )
[ hypericaceae ( clusiaceae ) ] is an amazonian plant traditionally used by indigenous population to treat dermatosis and inflammatory processes of the skin
time- or age-dependent accumulation of mitochondrial damage and dysfunction is strongly associated with aging [ @number@ ]
our results are in line with previous test-retest studies of [ ( @number@ ) c ] raclopride binding in the striatum
human [γ-crystallin] ( hgc ) , a water soluble protein present in the lens is known to aggregate with aging
moreover , we quantified levels of cellular senescence by senescence-associated β galactosidase ( [sa-βgal] ) assay
the soluble [aβ] are known to be more neurotoxicthan fibrillar aβ species
capsaicin was unable to provoke apoptotic cell death when used up to @number@ [μm] concentrations
before diagnosis , cases posed [€] @number@ more health costs per year than controls
excess health costs in the @number@ years around diagnosing and treating tb were [€] @number@ 
cases received an average excess public transfer income of [€] @number@ before vs [€] @number@ after diagnosis
average employment income deficiency was [€] @number@ before vs [€] @number@ after diagnosis , but the increasing difference showed a linear shape throughout the period
whether these are early features of pd will require a longitudinal study . [©] @number@ international parkinson and movement disorder society
in contrast , increasing the concentrations of celf1 inhibited formation of the [ hur / myc mrna ] complex
notably , phosphorylation of akt ( s473 ) and mobilization of [ ca2 + ] i caused by fmlf was inhibited by compound @number@ 
calcein acetyoxymethyl ester ( calcein am ; @number@ [μm] ) was added for @number@ min as the reporting molecule
positive controls were @number@ [μm] verapamil and @number@ [μm] digoxin
both children and adults had higher sensitivity at @number@.5 [°] / s compared to @number@.6 [°] / s ( paired t-tests , p < 0.05 )
results were extended to the european early-onset dementia cohorts ( @number@ early-onset alzheimer's disease [ eoad ] patients and @number@ nonaffected individuals )
ten subjects underwent an additional [ ( @number@ ) c ] pib pet scan within @number@ weeks
compared with [ ( @number@ ) c ] pib , [ ( @number@ ) f ] thk-5117 retention was higher in the medial temporal cortex
conclusion : these findings suggest that [ ( @number@ ) f ] thk-5117 provides regional information on neurofibrillary pathology in living subjects
their average monthly salary was @number@ ± @number@ [€] ( range : @number@ to @number@ [€] )
the mean total cost of care was @number@ ± @number@ [€] ( range : @number@ to @number@ [€] )
aggregation occurred in the temperature range 35-45 [°c] , in which the mutant protein began to lose the native conformation of its n-terminal domain
protected area coverage of aze sites is a key indicator of progress towards target @number@ [ @number@ ]
however , averting human-induced species extinctions within aze sites requires enhanced planning tools to increase the chances of success [ @number@ ]
slope at l5 was steeper than other levels ( @number@.7°±10.5 [°] , p < .0001! )
herein , a practical radiosynthesis of [ ( @number@ ) f ] cabs13 was achieved by radiofluorination followed by deprotection of an o-benzyloxymethyl group
finally , none of these parameters showed a significant association with voxelwise [ ( @number@ ) i ] fp-cit uptake
static pressure at @number@ % of fvc [ pst ( l ) 50 % ] was estimated based on age
ten frail aged adults ( frail group [ fg ] ) and ten young subjects ( young group [ yg ] ) performed the tug
results : seventy-seven patients ( mean age @number@.5±6.4 years , sex ratio @number@ [ male / female ] ) were analyzed
these phenotypes are more heritable ( [ formula : see text ] ) than gene expression levels
we quantified striatal and extrastriatal da d1 receptor density with [ ( @number@ ) c ] sch23390 and positron emission tomography in all participants
both atp and o2 ( - [•] ) / h2o2 are generated by electron transfer reactions
atp is the product of oxidative phosphorylation whereas o2 ( [-•] ) is generated by singlet electron reduction of di-oxygen ( o2 )
however , o2 ( [-•] ) / h2o2 are only dangerous in large quantities
in addition , redox signaling mechanisms that control o2 ( - [•] ) / h2o2 genesis from these sites are discussed
total rna was extracted and analyzed using dermarray ( [®] ) cdna microarrays
significant association of cataract risk with highest versus the lowest category of serum ascorbate was found in general [ @number@ ( @number@.564-0.879 ) ]
deoxyribonucleic acid replication and protein synthesis using [ ( @number@ ) h ] - thymidine and [ ( @number@ ) s ] - methionine incorporation were measured
methodology : published studies using pubmed ( [©] ) database @number@ - @number@ have been analyzed
the association for short sleep was smaller ( and not statistically significant ) ( hr = @number@ [ @percent@ ci @number@ @number@ ] )
klingberg ( trends cogn sci 14 : 317-324 , @number@ ) ] , thereby , however , confounding adaptivity and exposure to varying task difficulty
a nonsignificant negative association was estimated for pmcoarse ( adjusted or = @number@ @percent@ ci : @number@ @number@ per @number@ [μg] / m3 )
enzalutamide ( xtandi ( [®] ) ) is an androgen receptor inhibitor that blocks several steps in the androgen receptor signalling pathway
it is observed that the @number@ [μm] pore size zr-si scaffolds support the strongest matrix mineralization , as confirmed by calcium deposition
( r , r ' ) [ ( r , r ' ) - mnf ] is a highly-selective β2 adrenergic receptor ( β2-ar ) agonist
early uptake of [ ( @number@ ) c ] - pittsburgh compound b ( epib , 0-6 minutes ) estimates cerebral blood flow
the median length of stay in the hospital was @number@ [ 3-6 ] days
untreated rats were used as a control ( no-treatment [ nt ] group )
intervention at @date@ was associated with a lower probability of recurrence ( hr @number@ ci [ @number@ @date@ ] )
the amounts of cml in raw and cooked butters were @number@ ± @number@ and @number@ ± @number@ [μg] / g , respectively
the level of hmf in cooked butters was @number@ ± @number@ [μg] / g
materials and methods : heparinized human blood samples were incubated with ibogaine ( @number@ and @number@ [μm] ) at 37°c for 1 h 
the dimensions of these devices vary from @number@ to @number@ mm in diameter and @number@ to @number@ [μm] in thickness
results : the average iodine intake of the group was @number@ ± @number@ [μg]
the average iodine intake of the patients with hypothyroidism and euthyroidism was @number@ [μg] and @number@ [μg] , respectively
the 1410-nm wavelength is optimal for superficial dermal treatments up to @number@ [μm] deep
overall , @number@ studies demonstrated significant reductions in delirium incidence ( odds ratio [ or ] , @number@ @percent@ ci , @number@.38-0.58 )
also , wrinkles on crow 's feet measured by primos compact ( [®] ) ( gfmesstechnik gmbh , germany ) reduced @percent@
hispidin , a metabolite of dk , strongly inhibited pak1 with the ic50 = @number@ [μm]
commercially available microelectrode arrays ( meas ) were placed in a solution of hydrogen peroxide at @number@ [°c] for a period of @number@ days
hiv infection was associated with lower odds of outside hospitalization ( or = @number@ [ @percent@ ci : @number@ @number@ ] )
the thermitight probe temperature was set between @number@ to @number@ [°c] and was maintained using the thermistor integrated electrode
the clinical endpoint was an epidermal temperature of @number@ [°c] . two blinded reviewers assessed photographs taken at baseline and @number@ days post-procedure
histological analysis showed focal damage that extended about @number@ [μm] deep to the surface
bvftd patients showed widespread decrements in [ ( @number@ ) c ] abp688 bpnd throughout frontal , temporal and subcortical areas
several regions were characterized only by decreased binding of [ ( @number@ ) c ] abp688
kstrength60 [°] , age , and level of physical activity explained @percent@ of mgs variance ( p < @number@ ) in the global model
conclusions : regardless of the model , kstrength60 [°] was the best predictor of mgs in rural female older adults
trec was systematically higher than tint by @number@ [°c] ( @percent@ ci : @number@ @date@ [°c] )
participants placed their forearms on a passive motion apparatus which extended the elbow joint at constant velocities between @number@ and @number@.35 [@number@.35°s] ( @number@ )
alzheimer disease ( ad ) is characterized by progressive hypometabolism on [ ( @number@ ) f ] - fluorodeoxyglucose positron emission tomography ( fdg-pet ) scans
in the gmfcs level iv-v group , there was an annual increase of @number@.4 [°] in the scoliosis cobb angle ( p = @number@ )
the thoracic kyphosis angle increased by @number@.2 [°] ( p = @number@ ) annually in the gmfcs level iv-v group
results : of @number@ patients enrolled ( mean @number@.7±6.2 years [ range 70-92 years ] ) , @number@ ( @percent@ ) completed the 28-day observation
basic functional mobility ( timed up and go test [ tug ] ) and sf36 health status were also measured
five species of them have been recorded in chinese pharmacopoeia with name hippocampus ( chinese name haima [ symbol : see text ] )
cervicovaginal cytokines were adjusted to total protein concentration [ pg / mcg protein ]
middle-aged and older men and women [ n = @number@ aged @number@ ± 7 ( sd ) yr ] underwent iwt
gdf11 inhibits the activity of the peroxisome proliferator-activated receptor [γ] ( ppar-γ ) by promoting its sumoylation
analysis included demographic details , clinical outcome ( glasgow outcome scale , modified rankin scale [ mrs ] ) , and repeat vascular imaging
copyright [©] @number@ john wiley & sons , ltd
residents reported feeling comfortable when indoor temperature approximated @number@ [°c] . as living room temperature increased , indoor thermal comfort decreased
the normality values ranged from @number@.7 [°] to @number@.3 [°] in the sagittal plane , and from @number@.6 [°] to @number@.2 [°] in the frontal plane
the objective of this systematic review was to evaluate current evidence for the efficacy of ginkgo biloba extract egb 761 ( [®] ) in dementia
[ this corrects the article on p . @number@ in vol . @number@ pmid : @number@ ]
fasting blood and 24-h urine samples are processed on the day of collection and stored at @number@ [°c] in a fully automated storage facility
requests for data and biomaterials can be submitted to the lifelines research office [ llscience@umcg.nl ]
the risk-adjusted annual decline was @percent@ ( hazard ratio , @number@ [ @number@.97-0.98 ] ) and was similar across all age and sex-race groups
adjustments of functional goals ( lines of defense [ lods ] ) were examined during rehabilitation from incontinence
a validated instrument was used to measure well-being and happiness [ oxford happiness inventory ( ohi ) ]
benefits may also extend to other special populations who experience pm impairments ( e , traumatic brain injury [ tbi ] , parkinson 's )
odds ratio ( or ) was reported ( @percent@ confidence interval [ ci ] )
the use of a vitamin d supplement ( @number@ [μg] per day ) recommended
procedures for data access , information on collaborations , publications and other details can be found at [ @url@ 
the group mean pa was @number@.6 [°] ± @number@.1 [°] ( @number@.4°-9.2 [°] )
the mean pa for men was @number@.7 [°] ± @number@.3 [°] ( @number@.4°-9.2 [°] ) , and for women it was @number@.5 [°] ± @number@.7 [°] ( @number@.8-6.0 [°] )
since @number@ the vaccine , zostavax ( [®] ) , has been licensed to prevent herpes zoster
results : one hundred adults with mci [ @number@ ( @number@ ) years ; @percent@ women ] were enrolled and analyzed
the cumulative incidence of pca mortality was @percent@ [ @percent@ confidence interval ( ci ) @number@ @number@ ] after @number@ years
specialized receptors ( rage , galectin 3 […] ) bind age
diabetic retinopathy is related to excessive secretion of vascular growth factor ( vascular endothelial growth factor [ vegf ] )
london : mit press , @number@ ]
journal of experimental psychology : human perception and performance , @number@ 1072-1089 , @number@ ]
neuropsychologia , @number@ 218-229 , @number@ ]
[ @number@ ] the authors could not show any significant improvement in constitutional or sexual symptoms in this group of men
the rs9349379 [ g ] allele was previously shown to be associated with lower risk of migraine and increased risk of myocardial infarction
moreover , a reduction in carbohydrate intake ( [≤9.5] g / d ) resulted in increased tl among ala carriers
currently there are no recommended levels of intake [ i , dietary reference intakes ( dris ) ] as there are for nutrients and fiber
viscosity and ph were measured at a temperature of @number@ [°c] in a thermostatic bath
the mean cobb angle of kyphosis in the analytic sample was @number@.3 [°] ( standard deviation = @number@ )
sirtuins ( sirts ) catalyze the nad ( + ) - dependent deacetylation of n ( [ε] ) - acetyl lysines on various protein substrates
furthermore , these marginal benefits come at a very high price of [€] 110'@number@ per treatment
we pooled the effect estimates ( hazards ratios [ hrs ] ) under a random effects model
laser treatment was performed with a smartxide dot fractional co2 laser ( deka laser technologies , inc . ) emitting a wavelength of @number@ [μm]
treatment levels ranged from @number@ mj to @number@ mj total energy delivered per laser treatment spot ( @number@ [μm] spot size )
forty-nine subjects ( mean age @number@ years [ sd : @number@ ] , @number@ females [ @percent@ ] ) completed the study without adverse effects
the lumbar spine range of motion was significantly different between individuals with and without sns ( @number@.4 [°] vs @number@.9 [°] , ρ < @number@ )
overall gms medicines costs are projected to rise to [€] 1.9bn by @number@ 
methods : patients with rp as well as age- and sex-matched controls underwent external cold provocation by exposure to @number@ [°c] water for @number@ minute
the primary outcome was cvd ( acute myocardial infarction [ ami ] , unstable angina , ischemic stroke , and heart failure )
when comparing the results for complex sounds to thresholds obtained for pure-tones in a previous study by heinrich and schneider [ ( @number@ )
it is well established that the cholesterol-transporter apolipoprotein [ε] ( apoe ) genotype is associated with the risk of developing neurodegenerative diseases
objective : muscle loss and metabolic changes occur with disuse [ i bed rest ( br ) ]
results : mean diameter of superficial epithelial cells increases with age ( @number@ [μm] per year ; p < @number@ )
the co-cultured hdfs exhibited increased expression of [sa-β-gal]
the increased expression of [sa-β-gal] indicated an accelerated aging process
the main outcome variable was the global cognitive score assessed using the mindstreams ( [®] ) mild cognitive impairment assessment , a computerized cognitive assessment
[ 18f ] - feppa pet scans were acquired on @number@ healthy subjects and analyzed using a full kinetic compartment analysis
a simulation of increased tspo density exposed minimal effect on variability and identifiability of [ 18f ] - feppa vt in wm-rois
we found no association between age and [ 18f ] - feppa vt in wm-rois
a genetic association was found between p.t96k and ftd-s ( p = @number@ odds ratio = @number@ @percent@ confidence interval [ @number@.17-14.77 ] )
we also revealed that pim-1 interacts with and phosphorylates heterochromatin protein 1 [γ] ( hp1 [γ] ) on ser93
l-arginine-hcl was continuously infused [ intravenously ( iv ) ] in three stepwise-increasing doses ( @number@ @number@ and @number@ μmol·kg-1·h-1 )
pha was calculated directly with its arctangent ( resistance / reactance×180 [°] / π )
in children , the mean ratio was @number@ ± @number@ and the mean choroidal vascular diameter was @number@ ± @number@ [μm]
in adults , the values were @number@ ± @number@ and @number@ ± @number@ [μm] , respectively
background : the apolipoprotein e ( apoe ) [ε4] genotype is associated with an increased risk of alzheimer's disease
objective : we examined whether a peroxisome proliferator-activated receptor [γ] ( ppar-γ ) agonist , pioglitazone , suppresses coronary spasm
b-pb levels in men were significantly higher than in women ( gm @number@.9 [μg] / l vs @number@.1 [μg] / l )
binding ratios of [ ( @number@ ) f ] fp-cit were obtained in the putamen and caudate using the occipital cortex as reference
thirty-three ( mean age [ sd ] = @number@ [ @number@ ] years ; @percent@ female ) older adults with slow gait participated
in our study , we identified a reduced frequency of γ / [δ] t cells but not α / β t cells with aging
men had lower 3 d l [ε] , 3drε , 3daε , and 2 d longitudinal strain than women ( p < @number@ )
vo ( 2p ) and [ hhb ] responses were modeled as a mono-exponential
plasma s-nitrosothiols were unchanged ( [@number@.79±4.81] nm to @number@.27±5.79 nm , p = 0.3 )
high-flow mediated ba dilation was unchanged ( [@number@.3±9.4] % to @number@.5±7.2 % , p = 0.2 )
cognitive performance was assessed using accuracy ratio : [ correct responses ] / [ total responses ]
overall rate of early and late complications as well as adverse events was lower with uma jeunesse® than juvéderm ( [®] )
results : average surface in the ccs @number@ group was @number@ [cm²] statistically different when compared to the starr group ( @number@ [cm²] )
the effect of phylloquinone supplementation ( @number@ [μg] / d ) for @number@ y on plasma ucmgp was determined among @number@ participants
we have reported that molecular hydrogen has potential as an effective antioxidant for medical applications [ ohsawa et al. , nat
@number@ ( @number@ ) 688-694 ]
cardiovascular disease diminished the mean cognitive score also among discordant twin pairs ( [β-estimate] = 1.10 , p-value = @number@ )
[ bmb reports @number@ 44 ( @number@ ) : 298-305 ]
background : hyaluronic acid ( ha ) fillers such as restylane ( [®] ) are frequently used for the correction of facial soft tissue defects
both [ f-18 ] fddnp micropet imaging and neuropathological analyses revealed decreased aβ burden after intracranial anti-aβ antibody administration
these results corroborate previous analyses of [ f-18 ] fddnp pet imaging in clinical populations
total antioxidant capacity of the formulation , estimated by frap was @number@ ± @number@ [μm] fe ( ii ) / g dry mass
conclusions : fibrillar aβ detected by [ ( @number@ ) c ] pib-pet increases over time even in nondemented older adults
age at onset ranged from @number@ to @number@ years ( mean [ sd ] age , @number@ [ @number@ ] years )
our series consisted of @number@ hospitalized patients with a mean [±] s d age of @number@ ± @number@ years enrolled in the gifa study
transcription intermediary factor 1 [γ] ( tif1 [γ] ) was suggested to play a role in erythropoiesis
however , how tif1 [γ] regulates the development of different blood cell lineages and whether tif1 [γ] is involved in human hematological malignancies remain to be determined
here we have shown that tif1 [γ] was a tumor suppressor in mouse and human chronic myelomonocytic leukemia ( cmml )
tif1 [γ] was almost undetectable in leukemic cells of @percent@ of cmml patients
a demethylating agent restored the normal epigenetic status of the tif1 g promoter in human cells , which correlated with a reestablishment of tif1 [γ] expression
results showed that @number@ × 10⁻¹-10 [μm] tenuigenin significantly promoted cell viability and reduced cell death
taste was identified as the most important meat quality attribute ( perceived as [ very ] important by @percent@ of the respondents )
bonding surface of blocks was polished through 1200-grit sic and air-abraded ( @number@ [μm] alumina , @number@.28mpa , 20 s )
spatiotemporal gait data were obtained as participants completed two walks across a @number@.6-m electronic walkway ( gaitrite ( [®] ) )
data were aligned on biological ages [ years from peak height velocity ( phv ) ] to control for maturity
we confirmed , using electron spin resonance , that p-ncp directly inhibited ho ( [•] ) and ( @number@ ) o ( @number@ )
twenty-four healthy volunteers completed 3-tesla magnetic resonance imaging and high-resolution [ ( @number@ ) c ] raclopride pet scans
results : the cohort ( aged @number@ ± @number@ years [ means ± sd ] ) had a mean a1c of @number@ ± @percent@
the [«] premature ageing [»] hypothesis proposes that the brain areas of alcoholics undergo deterioration similar to that observed in old age
the authors propose that cst ranges from @number@ [μm] to @number@ [μm] in normal eyes
methods : fibroblasts were cultured with and without ck ( @number@ [μm] , @number@ [μm] or @number@ [μm] ) for @number@ hours
the particles size was @number@ @number@ @number@ and @number@ [μm] , respectively , for suspensions containing na-cmc , ibuprofen alone , hpmc , and gg
specifically , zebrafish [β2aar] had a high binding affinity for phenylephrine , a classical α-adrenergic receptor agonist
results : we demonstrate here the role of aging , of inosine and of the il-2 receptor [γ] mutation in controlling p . falciparum induced inflammation
to develop such therapeutics , we initially screened a small chemical library and selected compound @number@ whose ic ( @number@ ) is about @number@ [μm]
dermal elasticity was measured using a non-invasive , in vivo suction skin elasticity meter , cutometer ( [®] )
results : the median [ interquartile range ( iqr ) ] annual moving-average bc concentration was @number@ ( @number@ @date@ ) microg / m3
chappell and hollander \ " offer an evidence-based policy prescription to meet the challenges […] [ of ] an aging society . \ " 
moderate intensity vo ( 2p ) and ∆ [ hhb ] kinetics were examined in @number@ young males ( @number@ ± @number@ years )
changes in ∆ [ hhb ] of the vastus lateralis muscle were measured by near-infrared spectroscopy
results : mean epithelial thickness at the central cornea was @number@ ± @number@ [μm]
hypertension ( htn ) is the most common disease found in patients in primary care [ jnc-7 guidelines
hyper @number@ ; 42 : 1206 . ]
athero @number@ ; 158 : 195-8 . ]
the activation state of nk cells , reflected by telomerase activity and intracellular interferon [γ] ( ifnγ ) content , was also measured
the median age was @number@ years ( interquartile range [ iqr ] @number@ @number@ )
bm mean value was around @number@ [μm] , with narrow limits of ranging in aggr but more extended individual limits
lp mean value was around @number@ [μm] , also with narrow limits of ranging in aggr and more extended individual limits
the sympathetic nerve fiber area and sympathetic index were found to be @number@ [mm²] and @number@ respectively
the average age of women having their first child has been rising in recent decades [ @number@ ]
frailty is a condition frequently associated with low serum 25 [ oh ] d levels
in addition , ur-13756 is an effective p38 inhibitor at @number@ [μm] in werner syndrome cells , as shown by immunoblot
the cells were shammed or irradiated with @number@ j / cm ( @number@ ) of uva irradiation and treated with @number@ [μg] / ml astragaloside
the aging condition was determined by histochemical staining of senescence-associated β-galactosidase ( [sa-β-gal] )
astragaloside treatment was shown to decrease the level of [sa-β-gal] compared with the uva group
the renal function of those with a high aix was lower than those with a low aix [ ( @number@ ± @number@ ) ml.min
( @number@ m ( @number@ ) ) ( @number@ ) ] vs ( @number@ ± @number@ ) ml.min
( @number@ m ( @number@ ) ) ( @number@ ) , p = @number@ ]
they were divided into two groups , with and without apoe4 [ e4 ( + ) and e4 ( - ) ]
mann-whitney u analysis showed no difference between dose : [ px ] among patients with lvef of less than @percent@ versus @percent@ or greater
however , adjusting for bmi attenuated this association [ hr : @number@ ( @percent@ ci : @number@ @number@ ) ]
results : the mean inner retinal layer thickness for the entire population was @number@ [μm]
eyes that received the @number@ [μg] dose were indistinguishable from controls
eyes with existing nv that received @number@ [μg] vegf trap at p22 exhibited substantial resolution of oir pathology at p45
seer-medicare-linked database ( @number@ white men and women aged ≥ @number@ with invasive melanoma [ regional and distant stages ] ; 1991-1999 ) was used
the subject of this study was the influence of schizophrenia on the amount of oh ( [•] ) in human serum blood
results : during a median follow-up of @number@ years ( 25th to 75th percentile , @number@.2-8.2 ] , @number@ ( @percent@ ) elderly patients died
t cells were activated for @number@ h with costimulation of @number@ iu / ml interleukin-2 ( il-2 ) and @number@ [μg] / ml of anti-cd28
results : one half of the participants were vitamin d deficient ( 25 [ oh ] d < @number@ ng / ml ) at baseline
cis- or trans-18 : 1n9 triglycerides ( @number@ [μm] ) caused no apparent changes in the numbers of viable progeny of wild-type n2 animals
gas exchange was analysed breath-by-breath and muscle deoxygenation ( ∆ [ hhb ] ) was measured with nirs
results : mpod at @number@.5 [°] and @number@.0 [°] between pairs and within single eyes was strongly correlated ( p < @number@ )
smoking and body mass index showed moderately inverse associations with mpod at @number@.0 [°] , and age was positively related to mpod at both eccentricities
( zanthalene [®] ) as an anti-itching cosmetic ingredient
objective : [ corrected ] to evaluate the efficacy and persistence of sgp-ha for the correction of nlfs for up to @number@ months
non-enzymatic damage to nuclear proteins has potentially severe consequences for the maintenance of genomic integrity [ @number@ ]
incubation ( 2-7 h ) of rat hippocampal slices with kynurenine ( @number@ [μm] ) resulted in continuous de novo synthesis of kyna
these effects were attenuated by bff122 and mimicked by exogenously applied kyna ( @number@ [μm] )
of those , @number@ subjects had fecal elastase-1 level below @number@ [μg] / g as a marker of severe pancreatic insufficiency
solid-organ transplant recipients have an elevated risk for some malignancies because of the requirement for immunosuppression [ @number@ ]
ptld incidence is high immediately after transplantation , decreases subsequently , and then rises again 4-5 years from transplantation [ @number@ ]
muscarinic receptor density was assessed autoradiographically using the non-selective radioligand [ ( @number@ ) h ] quinuclidinylbenzilate
the ed ( @number@ ) for glutamic acid and the @number@ established excitotoxins was 200- to 360-fold lower , varying from @number@ to @number@ [μm]
the @number@.5th and @number@.5th percentile interocular difference tolerance limits for average rnfl thickness were @number@ [μm] and @number@ [μm] , respectively
cgmp in turn increases ca2 + uptake into intracellular calcium stores thereby lowering [ ca2 + ] i and inducing vsmc relaxation and vasodilation
the reviscometer ( [®] ) rvm600 device is capable of measuring directionality of forces on the skin
the reviscometer ( [®] ) rvm600 was used to measure resonance-running time ( rrt ) every 10 ° from 0 ° to 350 °
results : the mean keratometry reading was @number@ diopter ( d ) [ @percent@ confidence interval ( ci ) : @number@.22-44.57 ]
the ocular spherical aberration ( @number@ [μm] / year ) and horizontal coma ( @number@ [μm] / year ) increased moderately with age
cognitive category [ normal , cognitive impairment without dementia ( cind ) , or dementia ] was assigned by a consensus panel
the striatal binding potential of non-displaceable [ ( @number@ ) i ] pe2i was calculated
carriers of the apolipoprotein e ( apoe ) - [ε4] genotype have been shown to have greater mesial temporal atrophy and poorer memory functions than non-carriers
results : a total of @number@ men [ mean age @number@ ( sd @number@ ) yrs ] had complete data on pain status
similar measurements were taken on the left side [ @number@ ( ± @number@ ) cm and @number@ ( ± @number@ ) cm ]
such findings provide the foundation for the model of hemispheric asymmetry reduction in older adults , or \ " harold \ " [ @number@ ]
simultaneous , competing masker digit streams were simulated at locations 15 [°] left and right of center
beta-catenin silencing demonstrated that wnt induction of cyclin d1 expression is [β-catenin] dependent
results : mean cct was @number@ [μm] with an s d of @number@ [μm] and a range of 415-695 μm
the mean age of patients ( @percent@ male ) was @number@ ( interquartile range [ iqr ] , 35-48 ) years
ultrasonographic cross-sectional area ranged from @number@ to @number@ [mm²]
wave speed is one of the key factors describing wave propagation in arteries [ @number@ ]
local wave speed is directly related to the arterial wall properties [ @number@ ]
all bonding areas were first sandblasted with @number@ [μm] al ( @number@ ) o ( @number@ ) ( @number@ mpa , @number@ s )
residents were prescribed a mean [±] s d @number@ ± @number@ medications
lumbar lateral radiograph , sagittal balance and spinal mobility determined with spinalmouse ( [®] ) and back muscle strength were measured
microglial activation can be quantified in vivo using ( r ) - [ ( @number@ ) c ] pk11195 and positron emission tomography
in all subjects 60-minute dynamic ( r ) - [ ( @number@ ) c ] pk11195 scans were acquired
the fixtures were separated at a velocity of @number@ mm / min in @number@ [μm] intervals to stretch the ccc to its rupture point
the k ( m ) values for nicotinamide are low and in the range of @number@ @number@ [μm]
[ o'neill et al
( @number@ ) ; am j med genet part a 143a : 1421-1430 ] with the diagnosis of neonatal progeroid syndrome ( nps )
eligible patients were females aged @number@ or over and @number@ or younger with cellulite with documented cellulite 1°-4 [°] according to the nürnberger score
the corrected paragraph appears in the correction . ] 
data from younger and older listeners in a prior investigation [ gordon-salant et al. 
method : the geriatric suicide ideation scale ( gsis ; [ heisel et al
this result was statistically homogeneous ( percentage of the total variation across studies due to heterogeneity [ i2 ] = @number@ )
results : mean ssa , st , and c7 translation ratio were respectively @number@.4 [°] ± @number@.1 [°] , @number@.8 [°] ± @number@.4 [°] , and @number@.1 [°] ± @number@.9 [°]
using @number@ [μm] of conjugated pt-nps , the lifespan of n2 and lb25 was maximally extended
treatment for five days with @number@ [μm] conjugated pt-nps decreased cytosolic and mitochondrial reactive oxygen species in n2 and lb25 to a similar extent
the ratio of [ nad ( + ) ] / [ nadh ] was very low in the whole body and mitochondria of control lb25
neuropsychologia , @number@ 1165-1170 , @number@ ]
values above @number@ [μg] / l were found in @percent@ of all males
ferritin values > 1000 [μg] / l were found in @number@ patients
nature 399 : 255-258 ]
skin microrelief parameters were evaluated using the visioscan ( [®] ) vc98 - sels @number@ from courage + khazaka
the kappa coefficients for intraobserver and interobserver agreements were substantial to excellent ( intraobserver [ @number@ ] and interobserver [ @number@.721 0.807 ] )
time-varying estimates of the autoregulation index [ ari ( t ) ] were obtained with an autoregressive-moving average model with coefficients expanded by orthogonal decomposition
all subjects underwent [ ( @number@ ) f ] - fluorodeoxy glucose ( fdg ) positron emission tomography studies
vo ( 2p ) and ∆ [ hhb ] were modeled with a mono-exponential
moreover , this adaptation showed a clear decline with advancing age , but only for peripheral auditory space ( beyond ±10 [°] from midline )
the findings indicate that specific isolated premarin ( [®] ) components differ in their ability to affect cognition and nachr expression
[ @number@ ] : neurobiol aging 30 : 717-730 )
objective : to compare cerebellar pc loss in et , with normal and tremor dominant parkinson 's disease [ pd ] control brains
ed.44 , 91-96 ]
proteomics7 , 370-377 ]
proteomics9 , 523-537 ]
total mortality was also increased ( @number@ [ @number@.2-3.3 ] )
serum 25-hydroxyvitamin d [ 25- ( oh ) d ] was assessed by radioimmunoassay at baseline and @number@ years later
the prevalence of unoperated cataract increased with age and was higher in women than men ( odds ratio [ or ] , @number@ )
costs per patient within @number@ months of therapy were [€] @number@ and [€] @number@ respectively
lifetime blindness and costs were @number@ years and [€] @number@ ( strategy @number@ ) and @number@ years and [€] @number@ ( strategy @number@ )
two new studies suggest a new role for 53bp1 as an inhibitor of hr [ @number@ ]
we studied @number@ aged normal ( an ) subjects , @number@ mcis and @number@ ads with pet using [ ( @number@ ) c ] bf-227
adjustment of vo ( 2p ) and delta [ hhb ] were modeled using a mono-exponential equation by non-linear regression
we screened @number@ patients ( @number@ males [ @percent@ ] and @number@ females [ @percent@ ] ) between @number@ and @number@ years of age
the difference in the risk of falls was not significant ( relative risk @number@ @percent@ confidence interval [ ci ] @number@.94-1.75 )
effect sizes were smaller and nonsignificant in females ( hr = @number@ cis [ @number@ @number@ ] )
thoracic kyphosis angle , lumbar lordosis angle , thoracic rom , lumbar rom and spinal inclination angle were measured using spinalmouse ( [®] )
all amt6s levels were creatinine standardized ( [ amt6s ] / [ creatinine ] ) , and the cci was calculated
background : vitamin d status is currently diagnosed by measuring serum 25-hydroxyvitamin d [ 25 ( oh ) d ]
measurements were obtained under dilated and natural viewing conditions ( for accommodative efforts ranging from @number@ to @number@ diopters [ d ] )
background & aims : healthcare-associated infections [ hai ] are common in elderly individuals and may be related to both nutritional deficiencies and immunosenescence
the mean dose of ritonavir was @number@ mg / day , while the fluticasone dose was @number@ [μg] / day
there were 717 ( @percent@ ) women and @number@ deaths of which @number@ [ @percent@ ] were cardiovascular related
elevated %bf was associated with reduced mortality from cardiovascular causes ( hr @number@ [ @number@ @date@ ] )
over @percent@ of the athletes were hypohydrated ( urine specific gravity [ usg ] ≥1.020 mg·dl ) based on their first morning urine sample
the [ oxyhb ] changes were measured with @number@ channels of nirs during vft
in contrast , [ oxyhb ] only continued to increase in the adult group
efficacy was assessed @number@ weeks posttreatment ( end of study visit [ eos ] )
both categorization models showed high correlation ( [γs] = @number@ p < @number@ ) and agreement ( kappa = @number@ p < @number@ )
the control group included @number@ males and @number@ females , aging from @number@ to @number@ years [ mean ( @number@ ± @number@ ) ]
hypotonicity-induced cytosolic ca²⁺ ( [ ca²⁺ ] ( i ) ) rise in ipsc-ecs was measured by confocal microscopy
results : mean calculated csfp was @number@ ± @number@ mm hg and mean sfct was @number@ ± @number@ [μm]
in univariate analysis , sfct increased by @number@ [μm] ( @percent@ confidence interval : @number@ @number@ ) for each mm hg increase in csfp
the rt was inversely and significantly related to mpod at @number@.0 [°] and at @number@.0 [°] from the foveal center , but not to central mpod
no participants were vitamin a or vitamin e deficient ; @percent@ had low serum zinc levels ( < 70 [μg] / d l )
european journal of cognitive psychology , @number@ 415-436 ]
further analysis of the data identified a relationship between alcohol intake and csf [ nad ( h ) ] and markers of inflammation
number of medications on discharge was also associated with recurrent falls [ or @number@ ( @number@.0-1.3 ) ] , but ddis were not
a group-based protein requirement was assessed by using a nonlinear mixed model of protein intake and l- [ 1-¹³c ] phenylalanine oxidation
mn to un latency difference to rf was greater in females than males ( @number@.19±0.15 [@number@.19±0.15ms] vs @number@.10±0.16 [@number@.10±0.16ms] , p = 0.007 )
dna methylation ( 5-methylcytosine [ 5mc ] ) is one of several epigenetic markers altered in alzheimer's disease ( ad ) brain
more recently , attention has been given to dna hydroxymethylation ( 5-hydroxymethylcytosine [ 5hmc ] ) , the oxidized form of 5mc
inflammatory markers ( crp , tumor necrosis factor-α [ tnf-α ] , and interleukin-6 ) were obtained by enzyme-linked immunosorbent assay
results : age was similar in [ llf & llm ] and [ slf & / or s slm ]
diabetes duration was longer in [ slf & / or s slm ] ( p @number@ )
hba1c was higher ( @percent@ ) in [ slf & / or s slm ] ( p @number@ )
the risk of dementia was elevated in mci cases ( hazard ratio [ hr ] @number@ p < @number@ ) compared with cn subjects
@number@ [μg] / ml trf treatment exhibited the highest cell proliferation capacity
the soluble [aβ] accumulate intracellularly and disturb the synaptic function
methods : twenty intubated infants [ aged 39-77 weeks post-menstrual age ( pma ) ] were studied after surgery during sevoflurane wash-out
this task was repeated ten times under two temporal conditions ( self-initiated [ si ] vs reaction-time [ rt ] )
results : the correlation between the pacslac and painad was high ( r = @number@ [ @percent@ ci : @number@.67-0.87 ] )
fcp at a concentration of @number@ [μg] ml ( @number@ ) significantly improved the life span and tolerance against thermally induced stress in c elegans
the ultimate uncertainty of the method ranged from @number@ to @number@ [°c] depending on the approach used
objectives : in @number@ and @number@ we demonstrated elevated blood harmane concentrations [ ha ] in essential tremor ( et ) cases
we now assessed whether blood [ ha ] were elevated in parkinson 's disease ( pd ) as well
methods : blood [ ha ] were quantified by high performance liquid chromatography
alternatively , [α-secretase] cleavage generates a soluble and neuroprotective fragment ( sappα ) while precludes the production of aβ
cell viability decreased in a concentration-dependent manner and the ic50 was determined as @number@ [μm] in mcf-7 and @number@ [μm] in hs578t cell
the quantification of these peptides was determined using a stable isotope [ ( @number@ ) n ] - labeled aβ1-40 internal standard
they varied from @number@ ± @number@.9 [°] at t2 to @number@ ± @number@.6 [°] at l1
secretion parameters were quantified by automated deconvolution , approximate entropy [ apen ] , spikiness , and diurnal properties
separately the non-linear effect of [θ°] on iopg cannot be ignored for reasons of precision
results : the median follow-up time was @number@ years [ interquartile range ( iqr ) @date@ years ]
rotavirus ( rv ) p [ @number@ ] is an unique genotype that infects neonates
in this study , we explored host mucosal glycans as a potential age-specific factor for attachment of p [ @number@ ] rvs
chronic disease already accounts for @percent@ of u.s . health-care costs , foreshadowing an unsustainable financial burden for the aging population [ @number@ ]
all the participants will receive instructions on simple home-based exercises , dietary protein , and vitamin d supplementation ( @number@ [μg] / d )
mean ( @percent@ confidence interval [ c.i . ] ) 
interleukin ( il ) - [1β] reportedly leads to accumulation of amyloid β via nitric oxide stress in vitro
however , the ccn1-treated mpcs did express a senescence marker ( [sa-βgal] )
step length was the only individual wwt parameter that predicted falls [ hazard ratio ( hr ) @number@ p = @number@ ]
soy sauce and coffee contained n ( [ε] ) - carboxymethyl-lysine ( cml )
when human cancer cells were treated with dna damaging agent , adriamycin ( @number@ [μg] / ml ) , p21 was induced following p53 induction
mean [ ± standard deviation ( sd ) ] age was @number@ ± @number@ years and @number@ % were women
osteoprotegerin ( opg ) , transforming growth factor-β1 ( tgf-β1 ) and [tgf-β2] are cytokines closely associated with bone metabolism
moreover , patients were not cognitively impaired [ spm sq ( short portable mental status questionnaire ) m ± sd = @number@ ± @number@ ]
adjusted odds ratios and @percent@ confidence intervals ( [ , ] ) for fp conversion were estimated using logistic regression models with generalized estimating equations
this deviation was measured as difference between chronological and the neuroanatomical age ( brain age gap estimation [ brainage ] )
twelve control subjects and @number@ pd patients were examined with pet using the 5-ht ( 1b ) - radioligand [ ( @number@ ) c ] az10419369
data are given as mean ± sd or median [ interquartile range ]
the 3-year overall failure risk ratio was @number@ [ @number@.38- @time@ ] in favor of ceramic inlays although not statistically significant
the economic burden of incident and prior fragility fractures was estimated at [€] @number@ billion
sporadic amyloid [β-protein] ( aβ ) - type caa is commonly found in elderly individuals and patients with alzheimer disease
patients were also stratified analyzed according to stone components ( calcium oxalate stones [ cos ] ; non-calcium oxalate stones [ ncos ] )
a second cohort included @number@ subjects [ @number@ cognitively normal and @number@ amnestic mild cognitive impairment ] recruited in montreal
mpod was measured at @number@ @number@ @number@ and @number@.75 [°] eccentricity from the foveal centre using a heterochromatic flicker photometry based densitometer instrument
tspo expression can be quantified in-vivo using the positron emission tomography ( pet ) radioligand [ ( @number@ ) f ] - feppa
each amts6 level was expressed as [ amts6 ] ( in ng ) / [ mg ] creatinine
@number@ ) there was no significant difference between men ( 20 ° ) and women ( @number@.8 [°] ) ( p = @number@ )
the mean pre-operative prostate volume was @number@ [cm³]
lymphocyte subsets [ t , natural killer ( nk ) and nkt ] were phenotyped by flow cytometry
optimistic women were still at lower risk of death compared to neutral women [ hr @number@ @number@ % ci ( @number@.74-0.97 ) ]
among participants with diabetes , worse cognitive performance was associated with metformin use ( @number@ [ @number@ @date@ ] )
results : the normal central foveal thickness in healthy indian eyes measured using spectralis oct was @number@ ± @time@ [΅m]
background : tryptophan metabolism through the kynurenine pathway includes @number@ vitamin b-6 [ pyridoxal @number@'-phosphate ( plp ) ] - dependent enzymes
decreased birth rates and longer lifespans indicate that the global population is aging , although rates of aging differ between countries [ @number@ ]
the gulf advocate group recommends following the u.s . centers for disease control and prevention ( cdc ) guidelines for pneumococcal vaccination [ @number@ ]
we found that the expression of peroxisome proliferator-activated receptor [γ] ( pparγ ) and thyroid hormone receptor trβ was significantly decreased at higher passages
both sexes displayed a near-plateau in the %δ [ hhb ] which occurred at an exercise intensity near the respiratory compensation point
sixty-two subjects ( mean age @number@ years , standard deviation [ sd ] ± @number@ years ) with knee oa participated in the study
several mechanisms explain these deleterious effects of haart on mitochondria , and evidence points to other mechanisms beyond the \ " pol- [γ] hypothesis . \ " 
linear regression analysis yielded a decline in bl thickness of @number@ [μm] per year
receiver operating characteristic curves for the ufov ( risk index [ ri ] and subtests 1-3 ) and trails b significantly predicted on-road outcomes
the demographics , apoe [ latin small letter open e ] 4 status , and vascular risk factors were compared in the @number@ subgroups
intercheck ( [®] ) is a computerized prescription support system ( cpss ) developed in order to optimize drug prescription for elderly people with multimorbidity
conclusions : the use of intercheck ( [®] ) was associated with a significant reduction in pims and new-onset potentially severe ddis
method : tract integrity was determined using quantitative diffusion magnetic resonance imaging tractography ( tract-averaged fractional anisotropy [ fa ] )
center of foot-pressure average displacement ( root mean square [ rms ] ; in millimeters ) was calculated
they accounted for over @percent@ of global deaths and @percent@ of the global disease burden in @number@ . [ @number@ ] 
increasing evidence suggest that phospholipase c [γ] plays a key role in cell migration and invasion
because of its role in cell growth and invasion , aberrant phospholipase c [γ] signalling can contribute to carcinogenesis
indeed , isoform specificity and toxicity represents a big hurdle in the development of phospholipase c [γ] small molecule inhibitors
it was suggested that glucose metabolism and body fat content depend on serum levels of 25-hydroxyvitamin d [ 25 ( oh ) d ]
the effect of age , sex , ethnicity , and diabetes status on sif420 [ kx0.5 , km0.5 ] was analyzed
sif420 [ kx0.5 , km0.5 ] was higher in girls than boys in patients with diabetes patients
however , there was no effect of sex or race on sif420 [ kx0.5 , km0.5 ] in subjects without diabetes
the so-called [«] testosterone deficiency syndrome [»] is a blend of nonspecific symptoms typical of the physiological process of aging
methods : cerebellar cortex was snap frozen and stored at - [80°c] in aliquots for biochemical analyses
results : of @number@ participants , @number@ ( @percent@ ) older adults had anemia at baseline [ corrected ]
results : the results show that subjects taking cynatine ( [®] ) hns showed statistically significant improvements in their skin when compared with placebo
conclusion : cynatine ( [®] ) hns is an effective supplement for improving skin in @number@ days or less
results : pro-sftpb nondetectable status was significantly associated with lung cancer risk [ or = @number@ @percent@ confidence interval ( ci ) @number@.24-27.48 ]
participants : @number@ older adults ( mean [ standard deviation ] age : @number@ [ @number@ ] years ; @percent@ women )
purpose : this study compared the efficacy of complicated grief therapy ( cgt ; shear , k . [ @number@ ]
complicated grief : a guidebook for therapists [ liberty version ]
[ @number@ ]
mean inner arterial and venous diameters were @number@ ± @number@ [μm] and @number@ ± @number@ [μm] , respectively
furthermore , hpls from older donors increased activity of senescence-associated beta-galactosidase ( [sa-βgal] )
bull . , @number@ 1915-1918 , @number@ ]
the baseline ddd was greater than @number@ [°c] in @percent@ of the patients
a ddd > 1 [°c] was associated with a reduced recovery rate
clear changes were evident between level and incline surfaces regardless of fall risk as defined by @number@ different objective balance measures [ corrected ]
the average rnfl thickness ( mean ± sd ) was @number@ ± @number@ [μm]
for every diopter change towards hyperopia , the average rnfl thickness increased by @number@ [μm]
rptc treated with @number@ [μm] cygak-oc for @number@ h induced accumulation of atp synthase β and ndufb8 , two calpain @number@ substrates
res . 39 ( @number@ ) , 889-894 ( @number@ ) ]
gln170 , which is located in another unstructured part of [γs] crystallin , showed a similar deamidation profile to that of gln92
( @number@ ) ; neurosci lett 440 : 340-343 ] as well as reduced telomere probe light intensity values in interphases [ jenkins et al
( @number@ ) ; neurobiol aging 31 : 765-771 ]
conclusion : mean subfoveal choroidal thickness in healthy adults is approximately @number@ [μm]
leg strength , serum [ 25 ( oh ) d ] and physical activity levels were measured